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1

Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm

Jeffrey H. Fair, Bruce A. Cairns, Michael LaPaglia, Jian Wang, Anthony A. Meyer, Hyung Kim, Seigo Hatada, Oliver Smithies, Larysa Pevny

Journal:

Year:

2003

Language:

english

File:

PDF, 2.57 MB

english, 2003

2

A mouse α-globin-related pseudogene lacking intervening sequences

Vanin, Elio F., Goldberg, Gregory I., Tucker, Philip W., Smithies, Oliver

Journal:

Year:

1980

File:

PDF, 578 KB

1980

3

Duplication within the haptoglobin Hp2 gene

Maeda, Nobuyo, Yang, Funmei, Barnett, Don R., Bowman, Barbara H., Smithies, Oliver

Journal:

Year:

1984

File:

PDF, 815 KB

1984

4

Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination

Smithies, Oliver, Gregg, Ronald G., Boggs, Sallie S., Koralewski, Michael A., Kucherlapati, Raju S.

Journal:

Year:

1985

File:

PDF, 623 KB

1985

5

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

Doetschman, Thomas, Gregg, Ronald G., Maeda, Nobuyo, Hooper, Martin L., Melton, David W., Thompson, Simon, Smithies, Oliver

Journal:

Year:

1987

File:

PDF, 384 KB

1987

6

Rapid Genotyping of Mice with Hemoglobinopathies and Globin Transgenes

J. Barry III Whitney, Aya Leder, Jada Lewis, Raymond A. Popp, Chris Paszty, Edward M. Rubin, W. Ronald Shehee, Tim M. Townes, Oliver Smithies

Journal:

Biochemical Genetics

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

7

Animal models of human genetic diseases

Oliver Smithies

Journal:

Trends in Genetics

Year:

1993

Language:

english

File:

PDF, 735 KB

english, 1993

8

Inactivation of the MouseHPRTLocus by a 203-bp Retroposon Insertion and a 55-kb Gene-Targeted Deletion: Establishment of New HPRT-Deficient Mouse Embryonic Stem Cell Lines

Hirohisa Tsuda, Catherine E. Maynard-Currie, Laura H. Reid, Takayuki Yoshida, Koji Edamura, Nobuyo Maeda, Oliver Smithies, Aya Jakobovits

Journal:

Year:

1997

Language:

english

File:

PDF, 1.76 MB

english, 1997

9

Regulation of Blood Pressure by the Type 1A Angiotensin II Receptor Gene

Masaki Ito, Michael I. Oliverio, Peter J. Mannon, Christopher F. Best, Nobuyo Maeda, Oliver Smithies and Thomas M. Coffman

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 498 KB

english, 1995

10

Unexpected relationships between four large deletions in the human β-globin gene cluster

Elio F. Vanin, Paula S. Henthom, Dimitris Kioussis, Frank Grosveld, Oliver Smithies

Journal:

Year:

1983

Language:

english

File:

PDF, 1.31 MB

english, 1983

11

A history of the human fetal globin gene duplication

Shen, Shi-hsiang, Slightom, Jerry L., Smithies, Oliver

Journal:

Year:

1981

Language:

english

File:

PDF, 1.32 MB

english, 1981

12

Molecular genetics of the apolipoprotein B gene in pigs in relation to atherosclerosis

Nobuyo, Maeda, Ebert, David L., Doers, Thomas M., Newman, Marsha, Hasler-Rapacz, Judith, Attie, Alan D., Rapacz, Jan, Smithies, Oliver

Journal:

Year:

1988

Language:

english

File:

PDF, 2.06 MB

english, 1988

13

Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension

John, S., Krege, J., Oliver, P., Hagaman,, Hodgin, J., Pang, S., Flynn, T., Smithies, O.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

14

Turning Pages (Nobel Lecture)

Oliver Smithies

Journal:

Year:

2008

Language:

english

File:

PDF, 3.65 MB

english, 2008

15

Multiple roles of adrenomedullin revealed by animal models

Kathleen M. Caron, Oliver Smithies

Journal:

Microscopy Research and Technique

Year:

2002

Language:

english

File:

PDF, 219 KB

english, 2002

16

Three-dimensional diffusion tensor microscopy of fixed mouse hearts

Yi Jiang, Kumar Pandya, Oliver Smithies, Edward W. Hsu

Journal:

Magnetic Resonance in Medicine

Year:

2004

Language:

english

File:

PDF, 1.26 MB

english, 2004

17

A simplified chloral hydrate electrophoresis system for analysis of biological membranes

Byron Ballou, Oliver Smithies

Journal:

Analytical Biochemistry

Year:

1977

Language:

english

File:

PDF, 586 KB

english, 1977

18

Importance of quantitative genetic variations in the etiology of hypertension

Smithies, Oliver, Kim, Hyung-Suk, Takahashi, Nobuyuki, Edgell, Marshall H

Journal:

Kidney International

Year:

2000

Language:

english

File:

PDF, 793 KB

english, 2000

19

Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice

Norwood, Victoria F, Morham, Scott G, Smithies, Oliver

Journal:

Kidney International

Year:

2000

Language:

english

File:

PDF, 653 KB

english, 2000

20

Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition

Athirakul, Krairerk, Kim, Hyung-Suk, Audoly, Laurent P, Smithies, Oliver, Coffman, Thomas M

Journal:

Kidney International

Year:

2001

Language:

english

File:

PDF, 113 KB

english, 2001

21

The structure and evolution of the human salivary proline-rich protein gene family

Hyung Suk Kim, Karen M. Lyons, Eiichi Saitoh, Edwin A. Azen, Oliver Smithies, Nobuyo Maeda

Journal:

Mammalian Genome

Year:

1993

Language:

english

File:

PDF, 1.29 MB

english, 1993

22

Mouse angiotensin receptor genesAgtrlaandAgtr1bmap to Chromosomes 13 and 3

Tammy E. MacTaggart, Masaki Ito, Oliver Smithies, Simon W. M. John

Journal:

Mammalian Genome

Year:

1997

Language:

english

File:

PDF, 1.61 MB

english, 1997

23

Mouse natriuretic peptide receptor 3 gene maps to proximal Chromosome 15

Olga V. Savinova, Naomichi Matsukawa, Oliver Smithies, Simon W.M. John

Journal:

Mammalian Genome

Year:

1997

Language:

english

File:

PDF, 877 KB

english, 1997

24

Science brick by brick

Smithies, Oliver

Journal:

Year:

2010

Language:

english

File:

PDF, 151 KB

english, 2010

25

10.1038/nm1001-1083

Smithies, Oliver

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 4.86 MB

english, 2001

26

Essay: Many little things: one geneticist's view of complex diseases

Smithies, Oliver

Journal:

Nature Reviews Genetics

Year:

2005

Language:

english

File:

PDF, 1.38 MB

english, 2005

27

An Interview With...

Smithies, Oliver

Journal:

Nature Reviews Genetics

Year:

2005

Language:

english

File:

PDF, 82 KB

english, 2005

28

Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-α knock-out mice

K. Bridget Brosnihan, Jeffrey B. Hodgin, Oliver Smithies, Nobuyo Maeda, Patricia Gallagher

Journal:

Experimental Physiology

Year:

2008

Language:

english

File:

PDF, 428 KB

english, 2008

29

Therapeutic benefits in thalassemic mice transplanted with long-term−cultured bone marrow cells

Seigo Hatada, William Walton, Tomoko Hatada, Anne Wofford, Raymond Fox, Naiyou Liu, Michael C. Lill, Jeffery H. Fair, Suzanne L. Kirby, Oliver Smithies

Journal:

Experimental Hematology

Year:

2011

Language:

english

File:

PDF, 2.47 MB

english, 2011

30

Human genetics, animal models and computer simulations for studying hypertension

Nobuyuki Takahashi, Oliver Smithies

Journal:

Trends in Genetics

Year:

2004

Language:

english

File:

PDF, 215 KB

english, 2004

31

A Simple Hemagglutination System Requiring Small Amounts of Red Cells and Antibodies

Thomas G. Wegmann, Oliver Smithies

Journal:

Transfusion (Wiley)

Year:

1966

Language:

english

File:

PDF, 701 KB

english, 1966

32

Impaired T Cell Function in RANTES-Deficient Mice

Yasuhiko Makino, Donald N. Cook, Oliver Smithies, Olivia Y. Hwang, Eric G. Neilson, Laurence A. Turka, Hiroshi Sato, Andrew D. Wells, Theodore M. Danoff

Journal:

Clinical Immunology

Year:

2002

Language:

english

File:

PDF, 126 KB

english, 2002

33

Genotype/Age Interactions on Aggressive Behavior in Gonadally Intact Estrogen Receptor β Knockout (βERKO) Male Mice

Masayoshi Nomura, Larissa Durbak, Johnny Chan, Oliver Smithies, Jan-Åke Gustafsson, Kenneth S. Korach, Donald W. Pfaff, Sonoko Ogawa

Journal:

Hormones and Behavior

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

34

Two distinct apolipoprotein B alleles in mice generated by a single ‘in-out’ targeting

Lori R. Toth, Terry J. Smith, Caroline Jones, Harshini V. de Silva, Oliver Smithies, Nobuyo Maeda

Journal:

Year:

1996

Language:

english

File:

PDF, 892 KB

english, 1996

35

Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development

Nicola J.A. Scott, Leigh. J. Ellmers, John G. Lainchbury, Nobuyo Maeda, Oliver Smithies, A. Mark Richards, Vicky A. Cameron

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2009

Language:

english

File:

PDF, 907 KB

english, 2009

36

TRANSGENE-INDUCED ENHANCEMENT OF HEMATO-VASCULAR DIFFERENTIATION FROM MURINE EMBRYONIC STEM CELLS

Jennifer Bushman, Dominic Ciavatta, Oliver Smithies, Suzanne Kirby

Journal:

Cardiovascular Pathology

Year:

2004

Language:

english

File:

PDF, 19 KB

english, 2004

37

Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences

Stephanie M. Cohen, Seigo Hatada, Bruna P. Brylawski, Oliver Smithies, David G. Kaufman, Marila Cordeiro-Stone

Journal:

Year:

2004

Language:

english

File:

PDF, 455 KB

english, 2004

38

Using PAC nested deletions to order contigs and microsatellite markers at the high repetitive sequence containing Npr3 gene locus

Rodney C Gilmore, Joseph Baker Jr., Sean Dempsey, Rosemarie Marchan, Robert N.L Corprew Jr., Goldie Byrd, Nobuyo Maeda, Oliver Smithies, Richard D Bukoski, Ken R Harewood, Pradeep K Chatterjee

Journal:

Year:

2001

Language:

english

File:

PDF, 238 KB

english, 2001

39

Renin Cells Are Precursors for Multiple Cell Types that Switch to the Renin Phenotype When Homeostasis Is Threatened

Maria Luisa S Sequeira López, Ellen S Pentz, Takayo Nomasa, Oliver Smithies, R.Ariel Gomez

Journal:

Developmental Cell

Year:

2004

Language:

english

File:

PDF, 655 KB

english, 2004

40

Altering the Expression in Mice of Genes by Modifying Their 3′ Regions

Masao Kakoki, Yau-Sheng Tsai, Hyung-Suk Kim, Seigo Hatada, Dominic J Ciavatta, Nobuyuki Takahashi, Larry W Arnold, Nobuyo Maeda, Oliver Smithies

Journal:

Developmental Cell

Year:

2004

Language:

english

File:

PDF, 439 KB

english, 2004

41

Male�female differences in fertility and blood pressure in ACE-deficient mice

Krege, John H., John, Simon W. M., Langenbach, Laura L., Hodgin, Jeffrey B., Hagaman, John R., Bachman, Eric S., Jennette, J. Charles, O'Brien, Deborah A., Smithies, Oliver

Journal:

Year:

1995

File:

PDF, 398 KB

1995

42

TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

Noreen C. Luetteke, Ting Hu Qiu, Robert L. Peiffer, Paula Oliver, Oliver Smithies, David C. Lee

Journal:

Year:

1993

Language:

english

File:

PDF, 9.36 MB

english, 1993

43

The kallikrein–kinin system in health and in diseases of the kidney

Kakoki, Masao, Smithies, Oliver

Journal:

Kidney International

Year:

2009

Language:

english

File:

PDF, 347 KB

english, 2009

44

Base substitutions, length differences and DNA strand asymmetries in the human GÎ³ and AÎ³ fetal globin gene region

Smithies, Oliver, Engels, William R., Devereux, John R., Slightom, Jerry L., Shen, Shi-hsiang

Journal:

Year:

1981

Language:

english

File:

PDF, 926 KB

english, 1981

45

A Mouse Model for β0-Thalassemia

Baoli Yang, Suzanne Kirby, Jada Lewis, Peter J. Detloff, Nobuyo Maeda and Oliver Smithies

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.17 MB

english, 1995

46

Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family

Saitoh, Eiichi, Kim, Hyung-Suk, Smithies, Oliver, Maeda, Nobuyo

Journal:

Year:

1987

Language:

english

File:

PDF, 1.13 MB

english, 1987

47

Coordinate modulation of transfected HSV thymidine kinase and human globin genes

Roginski, Raymond S., Skoultchi, Arthur I., Henthorn, Paula, Smithies, Oliver, Hsiung, Nancy, Kucherlapati, Raju

Journal:

Year:

1983

Language:

english

File:

PDF, 2.64 MB

english, 1983

48

Problems encountered in detecting a targeted gene by the polymerase chain reaction

Hyung-Suk, Kim, Popovich, Bradley W., Shehee, W.Ronald, Shesely, Edward G., Smithies, Oliver

Journal:

Year:

1991

Language:

english

File:

PDF, 723 KB

english, 1991

49

Molecular analysis of deletions in the human β-globin gene cluster: Deletion junctions and locations of breakpoints

Henthorn, Paula S., Smithies, Oliver, Mager, Dixie L.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.33 MB

english, 1990

50

A physical map of the human salivary proline-rich protein gene cluster covers over 700 kbp of DNA

Kim, Hyung-Suk, Smithies, Oliver, Maeda, Nobuyo

Journal:

Year:

1990

Language:

english

File:

PDF, 1.70 MB

english, 1990